SCHEMBL23926332

SCHEMBL23926332

Cc1ccc(OCc2ccccc2)c(C(=O)C2CCCCCN2C(=O)O)n1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.44
FKBP1A P62942 7/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.40
SGMS2 Q8NHU3 1/20 0.40
TP53 P04637 1/20 0.39
CPT2 P23786 1/20 0.39
CPT1A P50416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926331 0.96 MEN1 (0.44) APPFKBP1AMEN1KMT2ATP53
SCHEMBL30118945 0.89 KLK7 (0.49) APPFKBP1AMEN1KMT2APOLB
SCHEMBL23964598 0.89 KLK7 (0.49) APPFKBP1AMEN1KMT2APOLB
SCHEMBL24127946 0.88 KLK7 (0.49) APPFKBP1AMEN1KMT2APOLB
SCHEMBL30118914 0.85 KLK7 (0.52) MEN1KMT2APOLBTP53
SCHEMBL23926370 0.85 KLK7 (0.52) MEN1KMT2APOLBTP53
SCHEMBL30118942 0.84 SPHK2 (0.42) APPMEN1KMT2A
SCHEMBL23926339 0.84 SPHK2 (0.42) APPMEN1KMT2A
SCHEMBL30369839 0.81 KLK7 (0.43) APPFKBP1AMEN1KMT2APOLB
SCHEMBL23926327 0.80 SPHK2 (0.41) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4168408-A1 COMPOUNDS FOR AND METHODS OF TREATING DISEASES Alterity Therapeutics Limited (AU) 2023-04-26 EP disclosed
WO-2021253091-A1 COMPOUNDS FOR AND METHODS OF TREATING DISEASES Alterity Therapeutics Limited (AU) 2021-12-23 WO disclosed
US-11155547-B1 Compounds for and methods of treating diseases Alterity Therapeutics Limited (AU) 2021-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11155547-B1 Compounds for and methods of treating diseases HTT, SNCA, PARK7 APP 67/4885FKBP1A 708/4885MEN1 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.