Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19990855 | 0.81 | UBE2M (0.42) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL20009190 | 0.79 | POLB (0.43) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL19990942 | 0.75 | UBE2M (0.40) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL17956429 | 0.74 | PKLR (0.35) | UBE2MDCUN1D1PKLRGAATSHR | |
| SCHEMBL19990701 | 0.74 | UBE2M (0.39) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL20009193 | 0.73 | UBE2M (0.38) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL20009191 | 0.72 | UBE2M (0.37) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL19990700 | 0.72 | UBE2M (0.39) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 | |
| SCHEMBL17956463 | 0.72 | POLB (0.35) | UBE2MDCUN1D1PKLRMEN1KMT2A | |
| SCHEMBL20009194 | 0.70 | UBE2M (0.37) | UBE2MDCUN1D1HDAC1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698796-B1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | NOVARTIS AG (CH) | 2021-10-27 | — | — | EP | disclosed |