Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | PTGFR | P43088 | 2/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2391719 | 0.81 | KDM4E (0.43) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL1843947 | 0.79 | ERN1 (0.47) | TBXA2RESR1PTGS2PTGS1MIF | |
| SCHEMBL9515747 | 0.78 | PTGER3 (0.43) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL2388955 | 0.78 | ESR1 (0.47) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL9515758 | 0.78 | PTGER3 (0.43) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL2393450 | 0.74 | ESR1 (0.46) | PTGER3PTGER2PTGER1TBXA2RPTGFR | |
| SCHEMBL2389161 | 0.74 | ESR1 (0.43) | PTGER3PTGER2PTGER1PTGER4CA1 | |
| SCHEMBL6678566 | 0.73 | ESR1 (0.48) | PTGER3PTGER2PTGER1PTGER4CA1 | |
| SCHEMBL6668620 | 0.73 | ESR1 (0.48) | PTGER3PTGER2PTGER1PTGER4CA1 | |
| SCHEMBL4617979 | 0.72 | AKR1C2 (0.47) | TBXA2RESR1PTGS2PKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |