Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392799 | 0.81 | PTGER3 (0.38) | KDM4EALDH1A1PLA2G1BATG4BGAA | |
| SCHEMBL2394283 | 0.75 | PKM (0.54) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9515747 | 0.75 | PTGER3 (0.43) | KDM4EALDH1A1PLA2G1BATG4BSMN1; SMN2 | |
| SCHEMBL9515758 | 0.75 | PTGER3 (0.43) | KDM4EALDH1A1PLA2G1BATG4BSMN1; SMN2 | |
| SCHEMBL8179413 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL8179414 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6022444 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6022435 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL2388955 | 0.72 | ESR1 (0.47) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1405663 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |