Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 14/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 13/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 13/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392815 | 1.00 | ITGAL (0.49) | ITGALITGB2ICAM1SCN9ATMEM97 | |
| SCHEMBL2396100 | 0.94 | ITGAL (0.50) | ITGALITGB2ICAM1SCN9ATMEM97 | |
| SCHEMBL2396097 | 0.94 | ITGAL (0.50) | ITGALITGB2ICAM1SCN9ATMEM97 | |
| SCHEMBL12259801 | 0.88 | ITGAL (0.64) | ITGALITGB2ICAM1SCN9ATMEM97 | |
| SCHEMBL2392974 | 0.81 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2392987 | 0.81 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL12259802 | 0.81 | ITGAL (0.67) | ITGALITGB2ICAM1TMEM97CTNNB1 | |
| SCHEMBL2394297 | 0.80 | ITGAL (0.60) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2392908 | 0.77 | ITGAL (0.58) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2392902 | 0.77 | ITGAL (0.58) | ITGALITGB2ICAM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552205-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-alpha]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-08 | — | — | US | disclosed |
| US-20110224188-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224188-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | HPGDS, COL14A1, ARG1 | ITGAL 74/4885ITGB2 346/4885ICAM1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.