SCHEMBL23928348

SCHEMBL23928348

CC(C)(C)c1cc(-c2cc(Cl)cc(-c3nc(-c4ccccc4-c4ccccc4)nc(-c4ccccc4-c4ccccc4)n3)c2)cc(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
RXRA P19793 3/20 0.40
RXRB P28702 3/20 0.40
RXRG P48443 2/20 0.37
CNR1 P21554 3/20 0.36
CNR2 P34972 2/20 0.35
LMNA P02545 1/20 0.35
NR1I3 Q14994 1/20 0.33
ACLY P53396 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23928341 0.99 KDM4E (0.41) KDM4EGAAMAPTRXRARXRB
SCHEMBL23928345 0.90 MAPT (0.47) KDM4EGAAMAPTRXRARXRB
SCHEMBL23959675 0.90 MAPT (0.47) KDM4EGAAMAPTRXRARXRB
SCHEMBL23959697 0.87 RXRA (0.50) KDM4EGAAMAPTRXRARXRB
SCHEMBL23928332 0.86 RXRB (0.49) KDM4EGAAMAPTRXRARXRB
SCHEMBL23928346 0.86 RXRA (0.47) KDM4EGAAMAPTRXRARXRB
SCHEMBL25823096 0.85 MAPT (0.51) KDM4EGAAMAPTRXRARXRB
SCHEMBL25823097 0.83 RXRB (0.50) KDM4EGAAMAPTRXRARXRB
SCHEMBL23959692 0.82 MAPT (0.55) KDM4EGAAMAPTRXRARXRB
SCHEMBL23928363 0.82 MAPT (0.55) KDM4EGAAMAPTRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563269-A Material for light-emitting device and electron-transporting layer, organic compound, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2021-10-29 CN disclosed
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-10-28 US disclosed
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210336151-A1 Light-Emitting Device Material, Electron-Transport Layer Material, Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, and Lighting Device SPIN3, SLC39A3, SKIC3 KDM4E 4238/4885GAA 4247/4885MAPT 1456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.