Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.41 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD5 | P21918 | 4/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239143 | 0.85 | DRD1 (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL23395314 | 0.77 | ESR1 (0.48) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL19457595 | 0.75 | DRD2 (0.47) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL23929169 | 0.73 | DRD2 (0.48) | DRD2DRD3 | |
| SCHEMBL25214790 | 0.72 | DRD2 (0.46) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL22970938 | 0.72 | MAOA (0.57) | DRD2DRD3DRD1 | |
| SCHEMBL23958536 | 0.71 | ESR1 (0.42) | DRD2DRD3 | |
| SCHEMBL13144731 | 0.71 | DRD2 (0.51) | DRD2DRD3HTR1DDRD1DRD4 | |
| SCHEMBL4084254 | 0.71 | DPP4 (0.43) | DRD2DRD3HTR1D | |
| SCHEMBL29672404 | 0.70 | CHRNA7 (0.45) | DRD2DRD3HTR1DDRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213358-A1 | BORON-CONTAINING COMPOUNDS AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |