Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306515 | 1.00 | CYP2C19 (0.50) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| SCHEMBL25950295 | 0.98 | CYP2C19 (0.52) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| SCHEMBL3927721 | 0.91 | — | — | |
| SCHEMBL21611688 | 0.85 | GAA (0.42) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| Octadecanoic Acid Amide SCHEMBL28253450 | 0.85 | SOAT1 (0.50) | CYP2C19CYP1A2MEN1KMT2ASOAT1 | |
| SCHEMBL24065981 | 0.84 | PAOX (0.55) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| SCHEMBL7389965 | 0.84 | PAOX (0.55) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| SCHEMBL23929253 | 0.84 | SOAT1 (0.53) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| SCHEMBL22834949 | 0.84 | SOAT1 (0.53) | CYP2C19CYP1A2PAOXMAOAMAOB | |
| SCHEMBL25185288 | 0.84 | SOAT1 (0.59) | CYP2C19CYP1A2PAOXMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168009-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | Hangzhou DAC Biotech Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |