Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | SAT1 | P21673 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929280 | 0.98 | CYP2C19 (0.50) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL16306515 | 0.98 | CYP2C19 (0.50) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL3927721 | 0.93 | — | — | |
| SCHEMBL3188929 | 0.85 | — | — | |
| Butyramide SCHEMBL28820281 | 0.85 | TSHR (0.58) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL13469009 | 0.84 | TSHR (0.52) | CYP2C19CYP1A2MEN1KMT2ATSHR | |
| Octadecanoic Acid Amide SCHEMBL28253450 | 0.82 | SOAT1 (0.50) | CYP2C19CYP1A2MEN1KMT2ATSHR | |
| SCHEMBL21611688 | 0.82 | GAA (0.42) | CYP2C19CYP1A2MEN1KMT2AGLA | |
| SCHEMBL23929253 | 0.82 | SOAT1 (0.53) | CYP2C19CYP1A2MEN1KMT2ATSHR | |
| SCHEMBL7389965 | 0.82 | PAOX (0.55) | CYP2C19CYP1A2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223783-A2 | FC CONTAINING POLYPEPTIDES WITH ALTERED GLYCOSYLATION AND REDUCED EFFECTOR FUNCTION | Genzyme Corporation (US) | 2023-08-09 | — | — | EP | disclosed |