Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887354 | 0.78 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084843 | 0.78 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL17127366 | 0.74 | ALDH1A1 (0.52) | PDE4DMEN1KMT2A | |
| SCHEMBL30084827 | 0.72 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2886497 | 0.72 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL18971592 | 0.68 | PDE4D (0.62) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL15760710 | 0.68 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL15790465 | 0.65 | PDE4B (0.49) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL6571713 | 0.65 | PDE4B (0.59) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL10210543 | 0.65 | PDE4A (0.42) | PDE4BPDE4DPDE4APDE4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022156727-A1 | COMPOSITION AND METHOD FOR TREATING TUMORS | 浙江养生堂天然药物研究所有限公司 | 2022-07-28 | — | — | WO | disclosed |
| WO-2021213455-A1 | DRUG COMBINATION AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |