Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 16/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 14/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.33 |
| ▸ | CASP1 | P29466 | 10/20 | 0.33 |
| ▸ | USP2 | O75604 | 10/20 | 0.33 |
| ▸ | CASP7 | P55210 | 9/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | GLA | P06280 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987360 | 1.00 | CYP1A2 (0.33) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL29986748 | 0.87 | CYP1A2 (0.35) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL23929340 | 0.83 | CYP1A2 (0.39) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL29987032 | 0.83 | CYP1A2 (0.39) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL23963529 | 0.83 | CYP1A2 (0.38) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL23929301 | 0.81 | CYP1A2 (0.34) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL29986491 | 0.81 | CYP1A2 (0.34) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL7222692 | 0.75 | HCAR1 (0.43) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL23929329 | 0.71 | CYP1A2 (0.41) | CYP1A2HSD17B10ALDH1A1CASP1USP2 | |
| SCHEMBL29987849 | 0.71 | CYP1A2 (0.41) | CYP1A2HSD17B10ALDH1A1CASP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549092-B | Tricyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2022-10-18 | — | — | CN | disclosed |
| WO-2021213460-A1 | TRICYCLIC KINASE INHIBITOR | 山东轩竹医药科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| CN-113549092-A | Tricyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |