Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 6/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 6/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877773 | 0.76 | GRIN2D (0.42) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL812216 | 0.74 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL4449687 | 0.71 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Ammonia Solution, Strong SCHEMBL14695768 | 0.71 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Memantine SCHEMBL249401 | 0.70 | GRIN1 (0.86) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL733849 | 0.69 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL3190483 | 0.69 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL3361 | 0.68 | GRIN1 (0.45) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL453075 | 0.68 | GRIN1 (0.45) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL28327525 | 0.68 | GRIN1 (0.45) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12486342-B2 | Cyclopentadienyl/adamantyl phosphinimine zirconium and hafnium complexes | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2025-12-02 | — | — | US | disclosed |
| US-12473384-B2 | Cyclopentadienyl/adamantyl phosphinimine titanium complexes | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2025-11-18 | — | — | US | disclosed |
| EP-4139320-B1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | NOVA CHEMICALS INTERNATIONAL SA (CH) | 2025-08-20 | — | — | EP | disclosed |
| EP-4139371-B1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE TITANIUM COMPLEXES | NOVA CHEM INT SA (CH) | 2024-08-14 | — | — | EP | disclosed |
| US-20230235100-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20230235100-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20230235100-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20230167205-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE TITANIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230167205-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE TITANIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-20230167205-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE TITANIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CN) | 2023-06-01 | — | — | US | disclosed |
| EP-4139320-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | Nova Chemicals (International) S.A. (CH) | 2023-03-01 | — | — | EP | disclosed |
| EP-4139371-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE TITANIUM COMPLEXES | Nova Chemicals (International) S.A. (CH) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214612-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021214629-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE TITANIUM COMPLEXES | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486342-B2 | Cyclopentadienyl/adamantyl phosphinimine zirconium and hafnium complexes | HCFC1, AP1M1, AP3M1 | GRIN1 1974/4885GRIN2A 4346/4885GRIN2D 3822/4885 |
| US-20230235100-A1 | CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES | HCFC1, AP1M1, AP3M1 | GRIN1 1974/4885GRIN2A 4346/4885GRIN2D 3822/4885 |
| US-12473384-B2 | Cyclopentadienyl/adamantyl phosphinimine titanium complexes | ACP1, CCT7, TCP1 | GRIN1 2519/4885GRIN2A 3859/4885GRIN2D 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.