Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.42 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929432 | 0.76 | GRIN1 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3842499 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5333489 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL26786757 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5463104 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2929198 | 0.73 | GRIN2D (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2826080 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1092580 | 0.73 | GRIN2D (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL21873554 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL26786761 | 0.73 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026104818-A1 | COMPLEX | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2026-05-21 | — | — | WO | claimed |
| US-12539508-B2 | Tri-(adamantyl) phosphines and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2026-02-03 | — | — | US | claimed |
| CN-119978004-A | Water-stable 2-pyridine inner salt boron reagent, preparation method thereof and application thereof in coupling reaction | 苏州大学 | 2025-05-13 | — | — | CN | claimed |
| CN-119409614-A | Difluoromethyl heteroarene compound and preparation method thereof | 国网安徽省电力有限公司电力科学研究院 | 2025-02-11 | — | — | CN | claimed |
| CN-118878402-A | Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage | 大连理工大学 | 2024-11-01 | — | — | CN | claimed |
| WO-2024173933-A2 | CATIONIC POLYMERS AND METHODS OF MAKING SAME, AND USES THEREOF | CORNELL UNIVERSITY (US) | 2024-08-22 | — | — | WO | claimed |
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117447394-A | Synthesis process of 2-isopropyl-4-methylpyridine-3-amine | 苏利制药科技江阴有限公司 | 2024-01-26 | — | — | CN | claimed |
| US-20240001353-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | UNIV PRINCETON (US) | 2024-01-04 | — | — | US | claimed |
| WO-2023243522-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | 日本化学工業株式会社 | 2023-12-21 | — | — | WO | claimed |
| WO-2009007012-A1 | PROCESS FOR SYNTHESIZING OLIGO/POLYTHIOPHENES BY A 'ONE-POT' SYNTHESIS ROUTE | BAYER TECHNOLOGY SERVICES GMBH (DE) | 2009-01-15 | — | — | WO | claimed |
| US-20080262183-A1 | Dithienopyrrole-containing copolymers | HONEYWELL INTERNATIONAL INC | 2008-10-23 | — | — | US | claimed |
| EP-1836184-A1 | IMPROVED PROCESS FOR THE KUMADA COUPLING REACTION | Honeywell International Inc. (US) | 2007-09-26 | — | — | EP | claimed |
| EP-1836233-A1 | HALOGENATED THIOPHENE MONOMER FOR THE PREPARATION OF REGIOREGULAR POLYTHIOPHENES | Honeywell International Inc. (US) | 2007-09-26 | — | — | EP | claimed |
| US-7262264-B2 | Halogenated thiophene monomer for the preparation of regioregular polythiophenes | HONEYWELL INTERNATIONAL INC. (US) | 2007-08-28 | — | — | US | claimed |
| US-7205414-B2 | Process for the Kumada coupling reaction | HONEYWELL INTERNATIONAL INC. (US) | 2007-04-17 | — | — | US | claimed |
| WO-2006076156-A1 | HALOGENATED THIOPHENE MONOMER FOR THE PREPARATION OF REGIOREGULAR POLYTHIOPHENES | HONEYWELL INTERNATIONAL INC. (US) | 2006-07-20 | — | — | WO | claimed |
| WO-2006076150-A1 | IMPROVED PROCESS FOR THE KUMADA COUPLING REACTION | HONEYWELL INTERNATIONAL INC. (US) | 2006-07-20 | — | — | WO | claimed |
| US-20060155105-A1 | Halogenated thiophene monomer for the preparation of regioregular polythiophenes | HONEYWELL INTERNATIONAL INC. | 2006-07-13 | — | — | US | claimed |
| US-20060155134-A1 | Process for the kumada coupling reaction | HONEYWELL INTERNATIONAL INC. | 2006-07-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539508-B2 | Tri-(adamantyl) phosphines and applications thereof | OTC, AOC3, ICOSLG | GRIN2D 1146/4885GRIN3B 1544/4885GRIN1 2528/4885 |
| US-20240001353-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | PADI3, ADA, ENTPD3 | GRIN2D 1090/4885GRIN3B 425/4885GRIN1 1542/4885 |
| US-20060155134-A1 | Process for the kumada coupling reaction | KMT5A, KMT5C, KCNT1 | GRIN2D 591/4885GRIN3B 664/4885GRIN1 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.