Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31731649 | 1.00 | LMNA (0.49) | LMNAMEN1PABPC1KMT2AMAPT | |
| SCHEMBL19200838 | 0.81 | LMNA (0.50) | LMNAMEN1PABPC1KMT2AMAPT | |
| SCHEMBL15749623 | 0.79 | POLB (0.49) | PGRMAOB | |
| SCHEMBL23957490 | 0.79 | CYP1A2 (0.54) | LMNAMEN1PABPC1KMT2AMAPT | |
| SCHEMBL19153391 | 0.72 | LMNA (0.47) | LMNAMEN1PABPC1KMT2AMAPT | |
| SCHEMBL29414385 | 0.71 | LMNA (0.56) | LMNAMAPTPGRMAOBADORA3 | |
| SCHEMBL1519715 | 0.71 | LMNA (0.56) | LMNAMAPTPGRMAOBADORA3 | |
| SCHEMBL2068622 | 0.70 | LMNA (0.67) | LMNAMEN1PABPC1KMT2AMAPT | |
| SCHEMBL1694027 | 0.69 | JAK2 (0.51) | — | |
| SCHEMBL24195933 | 0.69 | LMNA (0.53) | LMNAMEN1PABPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213929-A1 | PESTICIDALLY ACTIVE SUBSTITUTED 1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021213929-A1 | PESTICIDALLY ACTIVE SUBSTITUTED 1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2021-10-28 | — | — | WO | disclosed |