Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19199990 | 0.81 | CYP1A2 (0.54) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL23930346 | 0.79 | LMNA (0.49) | MEN1KMT2ALMNAPGRMAOB | |
| SCHEMBL31731649 | 0.79 | LMNA (0.49) | MEN1KMT2ALMNAPGRMAOB | |
| SCHEMBL7063351 | 0.77 | CYP1A2 (0.65) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL23930353 | 0.76 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL15749623 | 0.75 | POLB (0.49) | PGRMAOBPOLBB3GNT2 | |
| SCHEMBL22191016 | 0.74 | CYP1A2 (0.60) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL15999458 | 0.72 | PDE4A (0.44) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL6904350 | 0.71 | CYP1A2 (0.67) | CYP1A2MEN1KMT2ALMNACYP3A4 | |
| SCHEMBL6904502 | 0.71 | CYP1A2 (0.60) | CYP1A2MEN1KMT2ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213929-A1 | PESTICIDALLY ACTIVE SUBSTITUTED 1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2021-10-28 | — | — | WO | disclosed |