Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | PPARD | Q03181 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11338796 | 1.00 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL10892325 | 1.00 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL11141184 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL1162729 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL29073759 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL27694366 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL1396016 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28728956 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL11871477 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL7521011 | 0.96 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215501-A1 | MULTILAYER STRUCTURE, AND PACKAGING MATERIAL FOR RETORT USING SAME | 株式会社クラレ (JP) | 2021-10-28 | — | — | WO | disclosed |