Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445883 | 0.88 | DGKA (0.47) | DGKADNM1PAMTOP2AMAPT | |
| SCHEMBL19638 | 0.87 | DGKA (0.67) | DGKADNM1PAMMAPTMAPK1 | |
| SCHEMBL21891949 | 0.85 | DGKA (0.71) | DGKADNM1PAMMAPTMAPK1 | |
| SCHEMBL6449594 | 0.83 | CYP1A2 (0.57) | DGKAPAMCYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL19639 | 0.83 | DGKA (0.57) | DGKAPAMALDH1A1 | |
| SCHEMBL33810 | 0.83 | DGKA (0.74) | DGKADNM1PAMMAPTMAPK1 | |
| SCHEMBL28636584 | 0.82 | DGKA (0.47) | DGKADNM1PAMCYP1A2ALDH1A1 | |
| SCHEMBL10550073 | 0.82 | DGKA (0.55) | DGKAPAMALDH1A1 | |
| Bicarbonate SCHEMBL25246135 | 0.81 | DGKA (0.65) | DGKADNM1PAMTOP2AMAPT | |
| SCHEMBL5266225 | 0.81 | DGKA (0.65) | DGKADNM1PAMMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667244-B | 3-azabicycloalkyl derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-04-12 | — | — | CN | disclosed |
| US-20230203008-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LG CHEM, LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| EP-4134366-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Lg Chem, Ltd. (KR) | 2023-02-15 | — | — | EP | disclosed |
| CN-115667244-A | 3-azabicycloalkyl derivatives and pharmaceutical compositions comprising the same | 株式会社LG化学 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021215765-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 엘지화학 (KR) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203008-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADCY1, ADCY7 | DGKA 3279/4885DNM1 1363/4885PAM 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.