Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26977231 | 0.81 | MAP2K4 (0.34) | MAP2K4 | |
| SCHEMBL23930815 | 0.78 | RORC (0.37) | MAP2K4 | |
| SCHEMBL13210054 | 0.76 | MAP2K4 (0.36) | MAP2K4 | |
| SCHEMBL23930988 | 0.74 | MAP2K4 (0.31) | MAP2K4 | |
| SCHEMBL30833750 | 0.74 | MAP2K4 (0.39) | MAP2K4 | |
| SCHEMBL1321196 | 0.74 | MAP2K4 (0.39) | MAP2K4 | |
| SCHEMBL23930987 | 0.74 | MAP2K4 (0.31) | MAP2K4 | |
| Potassium Ion SCHEMBL1317651 | 0.73 | MAP2K4 (0.39) | MAP2K4 | |
| SCHEMBL21879928 | 0.72 | RHEB (0.31) | — | |
| SCHEMBL10143378 | 0.72 | MAP2K4 (0.34) | MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215545-A1 | ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | WO | disclosed |