Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27575238 | 0.90 | KMT2A (0.51) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL19099820 | 0.90 | KMT2A (0.51) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL531446 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL22323298 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL4473656 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL5268338 | 0.81 | SIGMAR1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL5268345 | 0.81 | SIGMAR1 (0.42) | MEN1KMT2AALDH1A1L3MBTL1HPGD | |
| SCHEMBL9470012 | 0.79 | ADRA2B (0.53) | MEN1KMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL1701279 | 0.78 | KMT2A (0.76) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL17557099 | 0.78 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013008-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |