SCHEMBL23932575

SCHEMBL23932575

Cc1ncnc(N2CCN(C(=O)O)CC2)c1I

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.40
ACHE P22303 1/20 0.39
BACE1 P56817 1/20 0.39
PIK3CA P42336 3/20 0.38
MTOR P42345 3/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 2/20 0.38
KIT P10721 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 2/20 0.37
RXFP1 Q9HBX9 1/20 0.37
LMNA P02545 3/20 0.37
HTT P42858 3/20 0.37
PDGFRB P09619 1/20 0.37
KMT2A Q03164 1/20 0.37
MEN1 O00255 1/20 0.36
P2RY12 Q9H244 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
LIMK2 P53671 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23932500 0.84 MAPT (0.41) MAPTACHEBACE1PIK3CAMTOR
SCHEMBL23932475 0.82 AKT1 (0.44) MAPTACHEBACE1PIK3CAMTOR
SCHEMBL25173918 0.82 MAPT (0.40) MAPTACHEBACE1PIK3CAMTOR
SCHEMBL23932590 0.81 KIT (0.52) MAPTALDH1A1KITSMN1; SMN2TSHR
SCHEMBL25187975 0.78 MAPT (0.40) MAPTACHEBACE1PIK3CAMTOR
SCHEMBL10320121 0.76 HTT (0.46) MAPTACHEBACE1MAPK1ALDH1A1
SCHEMBL23964298 0.74 HTR2C (0.50) MAPTALDH1A1KDM4ETSHRHTT
SCHEMBL12499419 0.74 KDM4E (0.51) PIK3CAMTORMAPK1ALDH1A1KDM4E
SCHEMBL29247593 0.73 LIMK2 (0.42) MAPTKITSMN1; SMN2TSHRRXFP1
Hydrochloric Acid SCHEMBL23932524 0.73 HTR2C (0.49) ALDH1A1KDM4ETSHRHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 MAPT 3388/4885ACHE 4885/4885BACE1 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.