Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960736 | 0.75 | USP2 (0.47) | NAMPT | |
| SCHEMBL29975368 | 0.74 | NAMPT (0.41) | NAMPTCNR2HDAC1HDAC2KCNH2 | |
| SCHEMBL25075681 | 0.74 | NAMPT (0.41) | NAMPTCNR2HDAC1HDAC2KCNH2 | |
| SCHEMBL29626816 | 0.73 | NAMPT (0.40) | NAMPTCNR2HDAC1HDAC2 | |
| SCHEMBL26907113 | 0.72 | TSHR (0.41) | HDAC1HDAC2TSHR | |
| SCHEMBL14880138 | 0.71 | SMN1; SMN2 (0.56) | TSHR | |
| SCHEMBL29619703 | 0.70 | NAMPT (0.44) | NAMPTCNR2HDAC1HDAC2 | |
| SCHEMBL25629294 | 0.69 | NAMPT (0.38) | NAMPTCNR2HDAC1HDAC2 | |
| SCHEMBL30900662 | 0.68 | MGLL (0.34) | CNR2HDAC1HDAC2 | |
| SCHEMBL15958454 | 0.68 | MEN1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4136118-A1 | ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF | Immunext, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021216913-A1 | ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF | IMMUNEXT, INC. (US) | 2021-10-28 | — | — | WO | disclosed |