Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975368 | 0.79 | NAMPT (0.41) | NAMPTHDAC1HDAC2VNN1CNR2 | |
| SCHEMBL25075681 | 0.79 | NAMPT (0.41) | NAMPTHDAC1HDAC2VNN1CNR2 | |
| SCHEMBL29626816 | 0.77 | NAMPT (0.40) | NAMPTHDAC1HDAC2VNN1CNR2 | |
| SCHEMBL25629294 | 0.73 | NAMPT (0.38) | NAMPTHDAC1HDAC2VNN1CNR2 | |
| SCHEMBL15750499 | 0.70 | CYP3A4 (0.40) | NAMPTHDAC1HDAC2VNN1 | |
| SCHEMBL31548277 | 0.70 | CNR2 (0.37) | NAMPTVNN1CNR2EPHX2 | |
| SCHEMBL23933127 | 0.70 | NAMPT (0.36) | NAMPTHDAC1HDAC2CNR2 | |
| SCHEMBL2960736 | 0.69 | USP2 (0.47) | NAMPTEPHX2 | |
| SCHEMBL15750497 | 0.69 | NAMPT (0.35) | NAMPTHDAC1HDAC2VNN1CNR2 | |
| SCHEMBL12735554 | 0.68 | POLB (0.50) | NAMPTVNN1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |