Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933220 | 1.00 | KDM4E (0.37) | KDM4EMEN1KMT2AALDH1A1CYP2A13 | |
| SCHEMBL1150375 | 0.84 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1CYP2A13 | |
| SCHEMBL15922897 | 0.67 | TP53 (0.41) | KDM4EMEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL25044952 | 0.64 | CYP2A13 (0.38) | KDM4EALDH1A1CYP2A13EPHX2 | |
| SCHEMBL15922741 | 0.64 | TP53 (0.39) | MEN1KMT2ASIGMAR1TP53MAPK1 | |
| SCHEMBL11355878 | 0.64 | HSD11B1 (0.41) | MEN1KMT2ASIGMAR1TP53MAPK1 | |
| SCHEMBL15922928 | 0.62 | HSD11B1 (0.43) | MEN1KMT2ATP53TSHRHTT | |
| SCHEMBL10436532 | 0.62 | HSD11B1 (0.43) | MEN1KMT2ATP53TSHRHTT | |
| SCHEMBL1143530 | 0.62 | TP53 (0.41) | MEN1KMT2AALDH1A1SIGMAR1TP53 | |
| SCHEMBL455945 | 0.59 | TP53 (0.36) | KDM4EMEN1KMT2AALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |