Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288373 | 1.00 | TSHR (0.32) | TSHRALOX15GABRR1GABRR2BLM | |
| SCHEMBL28628187 | 1.00 | TSHR (0.32) | TSHRALOX15GABRR1GABRR2BLM | |
| SCHEMBL28454873 | 0.83 | TSHR (0.33) | TSHRALOX15 | |
| SCHEMBL22288335 | 0.83 | TSHR (0.33) | TSHRALOX15 | |
| SCHEMBL25043435 | 0.81 | ALOX15 (0.32) | TSHRALOX15 | |
| SCHEMBL23613239 | 0.79 | ALOX15 (0.30) | TSHRALOX15 | |
| SCHEMBL25939837 | 0.79 | ALOX15 (0.30) | TSHRALOX15 | |
| SCHEMBL14762577 | 0.76 | TSHR (0.35) | TSHRALOX15LMNA | |
| SCHEMBL29210062 | 0.75 | TSHR (0.34) | TSHRALOX15 | |
| SCHEMBL262290 | 0.75 | MEN1 (0.39) | TSHRALOX15LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |
| CN-112300227-B | Heterocyclic amide compound, and preparation method and application thereof | 江西济民可信集团有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114174285-B | Heterocyclic amide compound, and preparation method and application thereof | 上海济煜医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116829551-A | Immunomodulatory antibody drug conjugates | 思进公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-113444023-B | Synthesis method and application of tert-butoxycarbonyl protected ammonia compound | 成都先导药物开发股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-112521371-B | Heterocyclic amide compound, pharmaceutically acceptable salt thereof, preparation method and application thereof | 中国药科大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-114174285-A | Heterocyclic amide compound and preparation method and application thereof | 上海济煜医药科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113549110-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113444023-A | Synthesis method and application of tert-butoxycarbonyl protected ammonia compound | 成都先导药物开发股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-109608443-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109071514-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-112300227-A | Heterocyclic amide compound and preparation method and application thereof | 江西济民可信集团有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-111499617-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111417630-A | Modulators of interferon gene stimulating factor (STING) | 葛兰素史克知识产权开发有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111194214-A | Methods of administering STING agonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-05-22 | — | — | CN | disclosed |