Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664150 | 0.83 | TSHR (0.37) | MEN1KMT2ATSHRMAPTCACNA1B | |
| SCHEMBL10702387 | 0.82 | KDM4C (0.38) | MEN1KMT2ATSHRMAPTCACNA1B | |
| SCHEMBL10720740 | 0.82 | SMN1; SMN2 (0.37) | MEN1KMT2ATSHRMAPTCACNA1B | |
| SCHEMBL23198789 | 0.81 | ALDH1A1 (0.41) | TSHRMAPTCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL14762577 | 0.81 | TSHR (0.35) | KMT2ATSHRALOX15LMNAGAA | |
| SCHEMBL29210062 | 0.79 | TSHR (0.34) | TSHRALOX15 | |
| SCHEMBL10187040 | 0.77 | MEN1 (0.33) | MEN1KMT2ATSHRMAPTCACNA1B | |
| SCHEMBL10187039 | 0.77 | SMN1; SMN2 (0.34) | MEN1KMT2ATSHRMAPTCACNA1B | |
| SCHEMBL10702150 | 0.77 | NAALAD2 (0.39) | MEN1KMT2ATSHRMAPTCACNA1B | |
| SCHEMBL22288335 | 0.76 | TSHR (0.33) | TSHRALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063324-A | Inhibitors of BTK and/or RET having macrocyclic structure | 赛诺哈勃药业（成都）有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-2443485-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2443486-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9198974-B2 | Decorated macromolecular scaffolds | MINTAKA FOUNDATION FOR MEDICAL RESEARCH (CH) | 2015-12-01 | — | — | US | disclosed |
| US-20140221569-A1 | DECORATED MACROMOLECULAR SCAFFOLDS | ORION BIOTECHNOLOGY HOLDING SA (CH) | 2014-08-07 | — | — | US | disclosed |
| US-8293715-B2 | 10a-Azalide compound crosslinked at 10a- and 12-positions | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8293715-B2 | 10a-Azalide compound crosslinked at 10a- and 12-positions | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| EP-2443485-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443486-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-7659307-B2 | Nonphytotoxic; 4-Bromo-3-methoxy-N-4-[4(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide; 4-[(Allyloxycarbonyl)amino]-3-methoxy-N-4-[4-(trifluoromethyl)phenoxy]phenyl-thiophene-2-carboxamide | BAYER CROPSCIENCE S.A. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-20080004287-A1 | Substituted Piperidines that Increase P53 Activity and the Uses Thereof | SCHERING CORPORATION | 2008-01-03 | — | — | US | disclosed |
| US-20080004287-A1 | Substituted Piperidines that Increase P53 Activity and the Uses Thereof | SCHERING CORPORATION | 2008-01-03 | — | — | US | disclosed |
| CN-1993362-A | Fused Heterocyclic Compounds | TAKEDA PHARMACEUTICAL (JP) | 2007-07-04 | — | — | CN | disclosed |
| EP-0579102-B1 | Liquid chromatography stationary phases with reduced silanol interactions | WATERS INVESTMENTS LTD (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0476564-B1 | Latent carbamate silicon coupling agents and process for preparation and use | OSI SPECIALTIES INC (US) | 1995-12-27 | — | — | EP | disclosed |
| US-5374755-A | Silica substrate with silanol surface groups blocked by (substituted)dialkylcarbamates | MILLIPORE CORPORATION (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0579102-A1 | Liquid chromatography stationary phases with reduced silanol interactions | WATERS INVESTMENTS LIMITED (US) | 1994-01-19 | — | — | EP | disclosed |
| EP-0476564-A1 | Latent carbamate silicon coupling agents and process for preparation and use | OSi Specialties, Inc. (US) | 1992-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004287-A1 | Substituted Piperidines that Increase P53 Activity and the Uses Thereof | TP53, MDM2, TP53BP1 | MEN1 3505/4885KMT2A 1308/4885TSHR 4670/4885 |
| US-20140221569-A1 | DECORATED MACROMOLECULAR SCAFFOLDS | ILK, HAVCR2, MATR3 | MEN1 3010/4885KMT2A 4620/4885TSHR 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.