Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28474102 | 0.86 | ITGB1 (0.39) | TSHRITGB1ITGA5ITGB3ITGB2 | |
| SCHEMBL7530545 | 0.86 | MAP3K14 (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| Bicarbonate SCHEMBL14918 | 0.86 | MAP3K14 (0.44) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| Propionic Acid SCHEMBL27332593 | 0.85 | FFAR3 (0.39) | TSHRITGB1ITGA5ITGB3ITGB2 | |
| Glycine SCHEMBL28308251 | 0.85 | GLRA1 (0.39) | TSHRITGB1ITGA5ITGB3ITGB2 | |
| Iodoacetic Acid SCHEMBL27900433 | 0.85 | ITGB1 (0.38) | TSHRITGB1ITGA5ITGB3ITGB2 | |
| Oxalic Acid SCHEMBL9728854 | 0.84 | MAP3K14 (0.43) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL15494454 | 0.83 | — | — | |
| SCHEMBL11288 | 0.83 | — | — | |
| Glutarate SCHEMBL28187765 | 0.83 | SLC22A6 (0.41) | TSHRITGB1ITGA5ITGB3ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4138875-A1 | RAS INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021217019-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-28 | — | — | WO | disclosed |