Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL17822302 | 0.92 | LMNA (0.41) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Glutarate SCHEMBL28187765 | 0.92 | SLC22A6 (0.41) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Octanedioate SCHEMBL6037701 | 0.91 | TSHR (0.43) | LMNATDP1MEN1KMT2ATSHR | |
| Butyric Acid SCHEMBL9430625 | 0.89 | FFAR3 (0.45) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Glutarate SCHEMBL25424321 | 0.88 | CAMK2A (0.38) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Bicarbonate SCHEMBL14918 | 0.87 | MAP3K14 (0.44) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Propionic Acid SCHEMBL27332593 | 0.86 | FFAR3 (0.39) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Glycine SCHEMBL28308251 | 0.86 | GLRA1 (0.39) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Chloroacetic Acid SCHEMBL23933671 | 0.86 | TSHR (0.39) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Iodoacetic Acid SCHEMBL27900433 | 0.86 | ITGB1 (0.38) | ITGB1ITGA5ITGB3ITGAVITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114438048-B | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118497161-A | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117866929-A | Pegylated arginine deiminase dimer preparation and use thereof | 重庆派金生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-114438048-A | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-111909906-A | Urate oxidase modified by polyethylene glycol | 重庆派金生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-114438048-B | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118497161-A | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-111909906-B | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117866929-A | Pegylated arginine deiminase dimer preparation and use thereof | 重庆派金生物科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114728254-A | Polyurea microcapsules and liquid surfactant system containing the same | 西姆莱斯股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114727914-A | Product for the indirect transfer of a cosmetic active to the skin | 西姆莱斯股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728092-A | Edge block with improved odor performance | 西姆莱斯股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113710331-A | Antimicrobial mixture | 西姆莱斯股份公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113543637-A | Antimicrobial mixture | 西姆莱斯股份公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113226267-A | Hair care composition | 西姆莱斯股份公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113164792-A | Liquid transparent mixtures of UV filters | 西姆莱斯股份公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113144174-A | Medicine for treating diseases related to high uric acid | 杭州远大生物制药有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112955230-A | A method for resisting female body odor | 西姆莱斯股份公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-111909906-A | Urate oxidase modified by polyethylene glycol | 重庆派金生物科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-110559472-A | Collagen-based medical adhesive and preparation method thereof | 陕西佰傲再生医学有限公司 | 2019-12-13 | — | — | CN | disclosed |