SCHEMBL23934138

SCHEMBL23934138

CC(=O)Oc1ccc(C(=O)Nc2ncc(N)s2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.61
HSD17B10 Q99714 1/20 0.61
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
NPC1 O15118 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
LMNA P02545 3/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
CSNK2A2 P19784 4/20 0.49
CSNK2A1 P68400 4/20 0.49
PKM P14618 2/20 0.46
HTT P42858 2/20 0.46
POLB P06746 1/20 0.46
RECQL P46063 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SCD O00767 1/20 0.46
MAPT P10636 1/20 0.44
TP53 P04637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13055699 0.84 RAB9A (0.57) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL2696655 0.83 RAB9A (0.56) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL13907037 0.82 RAB9A (0.58) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL705577 0.82 RAB9A (0.58) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL702024 0.81 RAB9A (0.57) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL12974286 0.80 RAB9A (0.72) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL13055708 0.77 RAB9A (0.53) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL25491131 0.77 ALDH1A1 (0.68) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL10114538 0.77 KMT2A (0.55) RAB9AHSD17B10KMT2AMEN1NPC1
SCHEMBL28316339 0.76 RAB9A (0.51) RAB9AHSD17B10KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3895706-A1 THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS Romark Laboratories, L.C. (US) 2021-10-20 EP disclosed