Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19355009 | 1.00 | OPRK1 (0.39) | OPRK1OPRM1OPRD1MEN1KMT2A | |
| SCHEMBL23934165 | 0.80 | TAAR1 (0.37) | OPRK1OPRM1OPRD1MEN1KMT2A | |
| SCHEMBL98648 | 0.75 | TAAR1 (0.49) | MEN1KMT2ATAAR1EPHX1SLC6A2 | |
| SCHEMBL18085425 | 0.74 | EPHX1 (0.46) | MEN1KMT2ATAAR1EPHX1ADH1B | |
| SCHEMBL14008050 | 0.73 | SLC6A2 (0.56) | OPRK1MEN1KMT2ATAAR1MAOB | |
| SCHEMBL14008049 | 0.73 | SLC6A2 (0.56) | OPRK1MEN1KMT2ATAAR1MAOB | |
| SCHEMBL19658356 | 0.73 | SLC6A2 (0.56) | OPRK1MEN1KMT2ATAAR1MAOB | |
| SCHEMBL23439942 | 0.73 | NPC1 (0.41) | OPRK1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7514198 | 0.72 | EPHX1 (0.41) | MEN1KMT2ATAAR1EPHX1ADH1B | |
| SCHEMBL7514207 | 0.72 | EPHX1 (0.41) | MEN1KMT2ATAAR1EPHX1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426654-B1 | DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION | HARVARD COLLEGE (US) | 2021-10-20 | — | — | EP | disclosed |