Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514198 | 1.00 | EPHX1 (0.41) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL18085425 | 0.78 | EPHX1 (0.46) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL14680898 | 0.75 | EPHX1 (0.57) | EPHX1TAAR1ALPIPKMPTGS1 | |
| SCHEMBL98648 | 0.75 | TAAR1 (0.49) | EPHX1TAAR1MEN1KMT2ASLC6A2 | |
| SCHEMBL23934144 | 0.72 | OPRK1 (0.39) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL19355009 | 0.72 | OPRK1 (0.39) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL7525598 | 0.71 | EPHX1 (0.40) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL24575922 | 0.71 | EPHX1 (0.51) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL7525591 | 0.71 | EPHX1 (0.40) | EPHX1TAAR1MEN1KMT2AADH1B | |
| SCHEMBL18085427 | 0.68 | ANPEP (0.40) | MEN1KMT2AADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906900-B1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | AJINOMOTO KK (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-6093846-A | BY REACTING WITH SPECIFIED OPTICALLY ACTIVE AMINES SUCH AS CIS-1-AMINO-2-INDANOL IN A SOLVENT, PRODUCING TWO DIASTEREOISOMERIC SALTS OF DIFFERING SOLUBILITY, FRACTIONAL CRYSTALLIZATION AND DECOMPOSING THE SALT WITH ALKALI OR ACID | AJINOMOTO CO., INC. (JP) | 2000-07-25 | — | — | US | disclosed |
| US-6028217-A | CHEMICAL INTERMEDIATE FOR RENIN INHIBITOR OR ENKEPHALINASE ENZYME INHIBITOR | AJINOMOTO CO., INC. (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0906900-A1 | A process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid | Ajinomoto Co., Inc. (JP) | 1999-04-07 | — | — | EP | disclosed |