Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755961 | 0.87 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1G6PD | |
| SCHEMBL703471 | 0.86 | MEN1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1G6PD | |
| SCHEMBL703165 | 0.82 | HSD17B1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4756952 | 0.82 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2G6PDKMT2A | |
| SCHEMBL4757983 | 0.80 | KDR (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4756132 | 0.76 | CCNE1 (0.63) | NPC1RAB9ASMN1; SMN2ALDH1A1G6PD | |
| SCHEMBL5836282 | 0.75 | CCNE1 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1G6PD | |
| SCHEMBL4755967 | 0.75 | CSNK2A2 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4756236 | 0.74 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL10114373 | 0.74 | GCK (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3895706-A1 | THIAZOLINIDE COMPOUNDS FOR TREATING NON-INFLUENZA VIRAL INFECTIONS | Romark Laboratories, L.C. (US) | 2021-10-20 | — | — | EP | disclosed |