Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.43 |
| ▸ | RELA | Q04206 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934204 | 0.88 | KDM4E (0.54) | KDM4ENPSR1RXFP1ALDH1A1NPC1 | |
| SCHEMBL23934271 | 0.82 | KDM4E (0.68) | KDM4ENPSR1RXFP1ALDH1A1NPC1 | |
| SCHEMBL23934267 | 0.77 | HPGD (0.53) | KDM4ENPSR1RXFP1ALDH1A1NPC1 | |
| SCHEMBL27099939 | 0.77 | POLB (0.50) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23934285 | 0.77 | ACE2 (0.48) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27099941 | 0.75 | ALDH1A1 (0.41) | KDM4ERXFP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL27099938 | 0.74 | KMT2A (0.49) | KDM4ENPSR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27100055 | 0.73 | ALOX15 (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23934284 | 0.72 | MAPT (0.53) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL27100057 | 0.72 | CA12 (0.49) | KDM4ERXFP1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912660-B2 | S6K1 protein kinase inhibitors as cancer therapeutics | XAVIER UNIVERSITY OF LOUISIANA (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210323919-A1 | S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS | XAVIER UNIVERSITY OF LOUISIANA | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323919-A1 | S6K1 PROTEIN KINASE INHIBITORS AS CANCER THERAPEUTICS | RPS6KA6, RPS6KA1, RPS6KA3 | KDM4E 1367/4885NPSR1 2238/4885RXFP1 2817/4885 |
| US-11912660-B2 | S6K1 protein kinase inhibitors as cancer therapeutics | RPS6KA6, RPS6KA1, RPS6KA3 | KDM4E 1367/4885NPSR1 2238/4885RXFP1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.