SCHEMBL23935762

SCHEMBL23935762

CC(COCC(O)C(C)(F)F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGD P52209 2/20 0.34
FOLH1 Q04609 2/20 0.32
NAALAD2 Q9Y3Q0 2/20 0.32
GABRR1 P24046 2/20 0.32
CYP1A2 P05177 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15910175 0.79 GABRR1 (0.46) FOLH1NAALAD2GABRR1CYP1A2TP53
SCHEMBL22780951 0.76 HSD17B10 (0.44) FOLH1NAALAD2GABRR1CYP1A2TP53
SCHEMBL18822342 0.75 PLA2G2C (0.40) FOLH1NAALAD2GABRR1CYP1A2
SCHEMBL28976448 0.74 GABRR1 (0.38) FOLH1NAALAD2GABRR1CYP1A2TP53
SCHEMBL18327244 0.72 FOLH1 (0.33) FOLH1NAALAD2GABRR1CYP1A2
SCHEMBL499938 0.70 GABRR1 (0.38) FOLH1NAALAD2GABRR1CYP1A2TP53
SCHEMBL15866578 0.69
SCHEMBL15701348 0.69
SCHEMBL156205 0.69
SCHEMBL2908572 0.68 GABRR1 (0.37) FOLH1NAALAD2GABRR1CYP1A2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896056-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-10-20 EP disclosed