Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 17/20 | 0.52 |
| ▸ | VEGFA | P15692 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19870978 | 0.88 | EPAS1 (0.53) | EPAS1VEGFA | |
| SCHEMBL19870977 | 0.83 | EPAS1 (0.70) | EPAS1VEGFA | |
| SCHEMBL23935871 | 0.82 | EPAS1 (0.52) | EPAS1VEGFA | |
| SCHEMBL23935869 | 0.81 | VEGFA (0.58) | EPAS1VEGFA | |
| SCHEMBL19870984 | 0.80 | EPAS1 (0.54) | EPAS1VEGFA | |
| SCHEMBL28425036 | 0.79 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL28426265 | 0.79 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL30136495 | 0.79 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL30136473 | 0.79 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL28425034 | 0.79 | EPAS1 (0.78) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268362-B1 | SUBSTITUTED PYRIDINES AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |