SCHEMBL23935830

SCHEMBL23935830

CN[C@@H](Cc1ccc(C(=O)CNO)c(OC)c1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
CAPN1 P07384 7/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.44
FPR2 P25090 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 2/20 0.40
ALOX15 P16050 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.39
PPARG P37231 2/20 0.39
PPARA Q07869 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22108673 0.85 LDHA (0.49) LDHACAPN1FPR2ALDH1A1ATM
SCHEMBL23935852 0.84 SLC7A5 (0.48) LDHACAPN1SMN1; SMN2LMNAHTT
SCHEMBL22108590 0.84 LDHA (0.50) LDHAFPR2ALDH1A1MEN1KMT2A
SCHEMBL29633970 0.84 LDHA (0.50) LDHAFPR2ALDH1A1MEN1KMT2A
SCHEMBL805254 0.82 LDHA (0.69) LDHASMN1; SMN2FPR2ALDH1A1ALOX15
SCHEMBL10065588 0.82 LDHA (0.69) LDHASMN1; SMN2FPR2ALDH1A1ALOX15
SCHEMBL22445012 0.82 LDHA (0.69) LDHASMN1; SMN2FPR2ALDH1A1ALOX15
SCHEMBL31267220 0.82 LDHA (0.69) LDHASMN1; SMN2FPR2ALDH1A1ALOX15
SCHEMBL22108989 0.79 FOS (0.59) LDHAALDH1A1ALOX15TDP1
SCHEMBL22108718 0.79 FOS (0.59) LDHAALDH1A1ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896056-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-10-20 EP disclosed