SCHEMBL23936177

SCHEMBL23936177

c1ccc(-c2nc(-c3ccccc3)c3cc(-c4ccc5c(c4)-c4ccccc4C(c4ccccc4)(c4ccccc4)C5(c4ccccc4)c4ccccc4)ccc3n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
ATM Q13315 2/20 0.46
WHR1 P49842 1/20 0.43
PIK3CD O00329 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
MTOR P42345 1/20 0.38
PIK3CG P48736 1/20 0.38
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
TLR9 Q9NR96 1/20 0.35
MAPT P10636 4/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 3/20 0.34
LMNA P02545 1/20 0.34
DPP4 P27487 4/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936215 0.92 KMT2A (0.48) KMT2AMEN1ATMWHR1NPC1
SCHEMBL23936717 0.89 MEN1 (0.53) KMT2AMEN1ATMWHR1MAPK1
SCHEMBL23936027 0.86 WHR1 (0.47) KMT2AMEN1ATMWHR1PIK3CD
SCHEMBL23936297 0.85 MEN1 (0.46) KMT2AMEN1ATMWHR1MAPK1
SCHEMBL23936775 0.83 KMT2A (0.49) KMT2AMEN1ATMPIK3CANPC1
SCHEMBL23936199 0.83 MEN1 (0.44) KMT2AMEN1ATMNPC1RAB9A
SCHEMBL23936695 0.82 MEN1 (0.41) KMT2AMEN1ATMMAPTALDH1A1
SCHEMBL23935976 0.82 MEN1 (0.42) KMT2AMEN1ATMNPC1RAB9A
SCHEMBL23936277 0.81 MEN1 (0.50) KMT2AMEN1ATMWHR1MAPT
SCHEMBL22186317 0.81 MEN1 (0.44) KMT2AMEN1ATMWHR1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed