SCHEMBL23936830

SCHEMBL23936830

CC1(O)c2ccccc2-c2ccccc2C1(C)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.52
THRB P10828 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 2/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
CASP1 P29466 1/20 0.40
CA7 P43166 1/20 0.40
RECQL P46063 1/20 0.40
BACE1 P56817 1/20 0.40
CA9 Q16790 1/20 0.40
EHMT2 Q96KQ7 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936829 0.87 PDK2 (0.46) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL2239449 0.83 PDK2 (0.52) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL30341830 0.83 PDK2 (0.52) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL19757718 0.82 PDK2 (0.60) PDK2THRBTDP1ALDH1A1CA1
SCHEMBL26438412 0.82 PDK2 (0.51) PDK2THRBTDP1CA1CA2
SCHEMBL27661545 0.82 PDK2 (0.44) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL18383337 0.77 PDK2 (0.44) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL21842337 0.77 PDK2 (0.56) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL283246 0.77 HTR2A (0.48) PDK2THRBTDP1ALDH1A1L3MBTL1
SCHEMBL4325901 0.77 PDK2 (0.56) PDK2THRBTDP1ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed