SCHEMBL23936829

SCHEMBL23936829

CC1(C)c2ccccc2-c2ccccc2C1(C)O

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.46
THRB P10828 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 2/20 0.39
HSP90AA1 P07900 1/20 0.39
HSP90AB1 P08238 1/20 0.39
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936830 0.87 PDK2 (0.52) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL26438407 0.84 PDK2 (0.47) PDK2THRBTDP1
SCHEMBL26438409 0.84 PDK2 (0.47) PDK2THRBTDP1
SCHEMBL26543952 0.82 PDK2 (0.36) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL18383337 0.82 PDK2 (0.44) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL29386757 0.82 PDK2 (0.44) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL25698875 0.80 ALDH1A1 (0.53) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL30341830 0.77 PDK2 (0.52) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL2239449 0.77 PDK2 (0.52) PDK2THRBTDP1ALDH1A1HSP90AA1
SCHEMBL23936836 0.74 THRB (0.44) PDK2THRBTDP1ALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed