Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23936729 | 0.83 | BCHE (0.68) | BCHEGNAI3GNAO1GNAI1 | |
| SCHEMBL12227016 | 0.81 | GNAI3 (0.58) | BCHEGNAI3GNAO1GNAI1ALOX15 | |
| SCHEMBL23936858 | 0.81 | GNAI3 (0.37) | GNAI3GNAO1GNAI1ALOX15ARG1 | |
| SCHEMBL21214172 | 0.80 | GNAI3 (0.38) | GNAI3GNAO1GNAI1SMN1; SMN2 | |
| SCHEMBL27285927 | 0.78 | BCHE (0.43) | BCHECHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL21423962 | 0.78 | BCHE (0.49) | BCHECHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL20996039 | 0.75 | BCHE (0.44) | BCHECHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL20994691 | 0.75 | BCHE (0.41) | BCHECHRNB2CHRNA4CHRNA7CHRNB4 | |
| SCHEMBL13346329 | 0.74 | — | — | |
| SCHEMBL28257297 | 0.74 | BCHE (0.43) | BCHECHRNB2CHRNA4CHRNA7CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |