SCHEMBL23936858

SCHEMBL23936858

NCCN1CC(C(=O)NI)C1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
ALOX15 P16050 1/20 0.34
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23936730 0.83 BCHE (0.49) GNAI3GNAO1GNAI1
SCHEMBL23936859 0.81 BCHE (0.45) GNAI3GNAO1GNAI1ALOX15ARG1
SCHEMBL21214172 0.77 GNAI3 (0.38) GNAI3GNAO1GNAI1
SCHEMBL23936819 0.69
SCHEMBL22916936 0.69
SCHEMBL3952181 0.67 GABRR1 (0.41) ALOX15ARG1ARG2
SCHEMBL27454271 0.66 BCHE (0.51)
SCHEMBL21423698 0.65 CHRNB2 (0.43)
SCHEMBL31421541 0.65 OGA (0.39) GNAI3GNAO1GNAI1ALOX15
SCHEMBL31420919 0.65 GNAI3 (0.35) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475277-B1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF BIOIMICS AB (SE) 2021-10-20 EP disclosed