Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 20/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | SNCA | P37840 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Florbetapir SCHEMBL29375540 | 1.00 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir SCHEMBL3356976 | 1.00 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir F 18 SCHEMBL14826096 | 1.00 | APP (1.00) | APPMAPTSNCA | |
| Florbetapir F 18 SCHEMBL29517039 | 1.00 | APP (1.00) | APPMAPTSNCA | |
| SCHEMBL13863151 | 0.92 | APP (0.85) | APPMAPTSNCA | |
| SCHEMBL15307628 | 0.92 | APP (0.85) | APPMAPTSNCA | |
| SCHEMBL15731546 | 0.90 | APP (0.81) | APPMAPTSNCA | |
| SCHEMBL13827030 | 0.90 | APP (0.81) | APPMAPTSNCA | |
| SCHEMBL12318871 | 0.90 | APP (0.81) | APPMAPTSNCA | |
| SCHEMBL13827059 | 0.88 | APP (0.79) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575898-B1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND | LIFE MOLECULAR IMAGING SA (CH) | 2020-09-30 | — | — | EP | disclosed |
| EP-2579902-B2 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2019-08-14 | — | — | EP | disclosed |
| EP-2590683-B1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2017-10-18 | — | — | EP | disclosed |
| EP-2579902-B1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2017-07-12 | — | — | EP | disclosed |
| EP-2363392-B1 | STYRYLPYRIDINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2017-05-03 | — | — | EP | disclosed |
| US-9592308-B2 | Method for production of F-18 labeled amyloid beta ligands | PIRAMAL IMAGING SA (CH) | 2017-03-14 | — | — | US | disclosed |
| US-20160184465-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2016-06-30 | — | — | US | disclosed |
| US-8981156-B2 | Method for production of F-18 labeled amyloid beta ligands | PIRAMAL IMAGING SA (CH) | 2015-03-17 | — | — | US | disclosed |
| US-8840866-B2 | Styrylpyridine derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-09-23 | — | — | US | disclosed |
| US-20140243533-A1 | METHOD FOR PRODUCTION OF F-18 LABELED A-BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2014-08-28 | — | — | US | disclosed |
| EP-2575898-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND | Piramal Imaging SA (CH) | 2013-04-10 | — | — | EP | disclosed |
| EP-1999109-B1 | STYRYLPYRIDINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2011151273-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151282-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151283-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | disclosed |
| US-7687052-B2 | radiolabeling; neurodegenerative diseases | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-30 | — | — | US | disclosed |
| US-20090123369-A1 | Styrylpyridine Derivatives and Their Use for Binding and Imaging Amyloid Plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-05-14 | — | — | US | disclosed |
| EP-1999109-A2 | STYRYLPYRIDINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees Of The University Of Pennsylvania (US) | 2008-12-10 | — | — | EP | disclosed |
| US-20080038195-A1 | radiolabeling; neurodegenerative diseases | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-02-14 | — | — | US | disclosed |
| WO-2007126733-A2 | STYRYLPYRIDINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184465-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | APP, APBA1, BACE1 | APP 1/4885MAPT 10/4885SNCA 9/4885 |
| US-20140243533-A1 | METHOD FOR PRODUCTION OF F-18 LABELED A-BETA LIGANDS | FOLR2, FOLR1, ADRA2A | APP 581/4885MAPT 2047/4885SNCA 232/4885 |
| US-20080038195-A1 | radiolabeling; neurodegenerative diseases | APP, PSEN1, HTT | APP 1/4885MAPT 6/4885SNCA 10/4885 |
| US-20090123369-A1 | Styrylpyridine Derivatives and Their Use for Binding and Imaging Amyloid Plaques | APP, APBA1, PSEN1 | APP 1/4885MAPT 7/4885SNCA 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.