Florbetapir

Florbetapir

SCHEMBL29375540

CNc1ccc(/C=C/c2ccc(OCCOCCOCCF)nc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APP P05067 20/20 1.00
MAPT P10636 1/20 1.00
SNCA P37840 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Florbetapir SCHEMBL3356976 1.00 APP (1.00) APPMAPTSNCA
Florbetapir F 18 SCHEMBL14826096 1.00 APP (1.00) APPMAPTSNCA
Florbetapir F 18 SCHEMBL29517039 1.00 APP (1.00) APPMAPTSNCA
Florbetapir F 18 SCHEMBL3356981 1.00 APP (1.00) APPMAPTSNCA
SCHEMBL13863151 0.92 APP (0.85) APPMAPTSNCA
SCHEMBL15307628 0.92 APP (0.85) APPMAPTSNCA
SCHEMBL15731546 0.90 APP (0.81) APPMAPTSNCA
SCHEMBL13827030 0.90 APP (0.81) APPMAPTSNCA
SCHEMBL12318871 0.90 APP (0.81) APPMAPTSNCA
SCHEMBL13827059 0.88 APP (0.79) APPMAPTSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120011879-A Alzheimer's disease multi-modal classification method based on electroencephalogram, brain image and genetic information 西北工业大学 2025-05-16 CN claimed
CN-116245833-B Prediction method for brain multi-mode PET image SUVR 复旦大学 2024-12-27 CN claimed
CN-116245833-A Prediction method for brain multi-mode PET image SUVR 复旦大学 2023-06-09 CN claimed
CN-114862774-A PET image cross-modal reconstruction method and device based on deep learning 浙江大学滨江研究院 2022-08-05 CN claimed
CN-114366824-A Probe for isotope targeted imaging and preparation method and application thereof 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 2022-04-19 CN claimed
CN-114202075-A Guided multi-mode image genetics data feature analysis method 河北工业大学 2022-03-18 CN claimed
CN-113978450-A Anti-heeling path tracking game control method for commercial vehicle 聊城大学 2022-01-28 CN claimed
CN-122071458-A Light-emitting element and amine compound for light-emitting element 三星显示有限公司 2026-05-22 CN disclosed
US-20260143965-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE LIGHT EMITTING ELEMENT, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO LTD (KR) 2026-05-21 US disclosed
US-12629094-B2 System, software and methods of using software for predicting efficacy of alzheimer's disease treatments THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
US-20260091109-A1 Method for Treating Alzheimer's Disease BIOGEN INT NEUROSCIENCE GMBH (CH) 2026-04-02 US disclosed
US-20250384559-A1 SYSTEM AND METHOD FOR SUBJECT-SPECIFIC AMYLOID POSITION EMISSION TOMOGRAPHY TRANSLATION USING CONDITIONED DIFFUSION-BASED GENERATIVE MODEL TATA CONSULTANCY SERVICES LIMITED (IN) 2025-12-18 US disclosed
EP-4663127-A1 SYSTEM AND METHOD FOR SUBJECT-SPECIFIC AMYLOID POSITRON EMISSION TOMOGRAPHY TRANSLATION USING CONDITIONED DIFFUSION-BASED GENERATIVE MODEL Tata Consultancy Services Limited (IN) 2025-12-17 EP disclosed
WO-2022072738-A1 SYSTEM, SOFTWARE AND METHODS OF USING SOFTWARE FOR PREDICTING EFFICACY OF ALZHEIMER'S DISEASE TREATMENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-07 WO disclosed
US-11292838-B2 Method for generating antibodies against T cell receptor MEDIGENE IMMUNOTHERAPIES GMBH (DE) 2022-04-05 US disclosed
CN-114202075-A Guided multi-mode image genetics data feature analysis method 河北工业大学 2022-03-18 CN disclosed
US-20220064271-A1 METHODS FOR TREATING TAUOPATHIES WASHINGTON UNIVERSITY 2022-03-03 US disclosed
US-20220051801-A1 CLASSIFYING NEUROLOGICAL DISEASE STATUS USING DEEP LEARNING THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2022-02-17 US disclosed
CN-114010641-A Methods for treating neurological disorders 爱普制药有限责任公司 2022-02-08 CN disclosed
CN-113978450-A Anti-heeling path tracking game control method for commercial vehicle 聊城大学 2022-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091109-A1 Method for Treating Alzheimer's Disease IGLV6-57, FCGR2A, BACE1 APP 4/4885MAPT 64/4885SNCA 66/4885
US-12629094-B2 System, software and methods of using software for predicting efficacy of alzheimer's disease treatments MAPT, APP, PSEN2 APP 2/4885MAPT 1/4885SNCA 13/4885
US-20260143965-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE LIGHT EMITTING ELEMENT, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT NR2E3, NR2E1, NR0B2 APP 3323/4885MAPT 2692/4885SNCA 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.