Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SAT1 | P21673 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932334 | 0.91 | KDM4E (0.43) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL4236221 | 0.88 | — | — | |
| SCHEMBL5933774 | 0.84 | ALDH1A1 (0.42) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL13822687 | 0.83 | CYP2C19 (0.58) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL13492945 | 0.81 | CYP2C19 (0.55) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL12380906 | 0.79 | CYP2C19 (0.52) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL1252986 | 0.78 | KDM4E (0.52) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL23633796 | 0.77 | ALOX15 (0.35) | TSHRKDM4EPOLBTHRBTDP1 | |
| SCHEMBL14930298 | 0.76 | TSHR (0.55) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL5932636 | 0.76 | TSHR (0.50) | CYP2C19MEN1GLAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473611-B1 | TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | ARBUTUS BIOPHARMA CORP (CA) | 2021-10-20 | — | — | EP | disclosed |