Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23937707 | 0.85 | GLO1 (0.32) | CA1CA2CA9CA12CA3 | |
| SCHEMBL21958617 | 0.84 | PTPN11 (0.32) | PTPN11CA1CA2CA12CA6 | |
| SCHEMBL20674481 | 0.83 | PTPN11 (0.33) | PTPN11 | |
| SCHEMBL20674517 | 0.81 | PTPN11 (0.33) | PTPN11CA1CA2CA12CA6 | |
| SCHEMBL20674099 | 0.75 | ADORA2A (0.35) | — | |
| SCHEMBL20674525 | 0.74 | CA1 (0.39) | CA1CA2CA9CA12CA3 | |
| SCHEMBL21958612 | 0.72 | PIM3 (0.35) | CA1CA2CA9CA12CA3 | |
| SCHEMBL20674103 | 0.70 | PAK1 (0.35) | — | |
| SCHEMBL20674518 | 0.70 | CA12 (0.33) | CA1CA2CA9CA12CA7 | |
| SCHEMBL23937705 | 0.69 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |