Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958535 | 0.81 | CNOT7 (0.33) | CNOT7 | |
| SCHEMBL21958537 | 0.78 | MAP3K14 (0.38) | CNOT7 | |
| SCHEMBL23937842 | 0.76 | BAZ2B (0.32) | TP53SMN1; SMN2BAZ2B | |
| SCHEMBL21955857 | 0.73 | FEN1 (0.37) | TP53SMN1; SMN2BAZ2BYTHDC1 | |
| SCHEMBL13485303 | 0.68 | NAMPT (0.53) | YTHDC1 | |
| SCHEMBL20631037 | 0.68 | KMT2A (0.38) | — | |
| SCHEMBL21958542 | 0.68 | ADORA3 (0.34) | TP53SMN1; SMN2BAZ2BYTHDC1 | |
| SCHEMBL1231822 | 0.67 | CFTR (0.36) | YTHDC1 | |
| SCHEMBL18337793 | 0.67 | CFTR (0.36) | YTHDC1 | |
| SCHEMBL21958625 | 0.67 | ERCC1 (0.36) | TP53SMN1; SMN2BAZ2BYTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |