Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20673904 | 0.86 | MAP2K2 (0.41) | NR4A2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20674231 | 0.83 | LMNA (0.43) | NR4A2ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL20674232 | 0.78 | BRD4 (0.45) | NR4A2ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL20631059 | 0.78 | KDM4E (0.35) | ALDH1A1KDM4EKMT2ABRD4MAPT | |
| SCHEMBL23937805 | 0.74 | KMT2A (0.35) | KMT2AGAA | |
| SCHEMBL1497913 | 0.71 | CNR2 (0.39) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL6481040 | 0.71 | MEN1 (0.56) | KMT2ALMNAMAPTMEN1GAA | |
| SCHEMBL20673887 | 0.71 | KMT2A (0.33) | KMT2A | |
| SCHEMBL20631038 | 0.71 | KMT2A (0.40) | ALDH1A1KDM4EHSD17B10TSHRKMT2A | |
| SCHEMBL13564517 | 0.70 | NR4A2 (0.69) | NR4A2ALDH1A1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |