Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631707 | 0.80 | GRIA2 (0.41) | LMNATSHRGAANPSR1TDP1 | |
| SCHEMBL20631124 | 0.76 | LMNA (0.36) | LMNATSHRGAANPSR1ALDH1A1 | |
| SCHEMBL21959600 | 0.75 | LMNA (0.34) | LMNATSHRGAANPSR1ALDH1A1 | |
| SCHEMBL20631145 | 0.74 | LMNA (0.30) | LMNA | |
| SCHEMBL20430159 | 0.73 | LMNA (0.51) | LMNATSHRGAANPSR1ALDH1A1 | |
| SCHEMBL14401055 | 0.73 | LMNA (0.55) | LMNATSHRGAANPSR1TDP1 | |
| SCHEMBL20371630 | 0.73 | TDP1 (0.59) | LMNATSHRGAANPSR1TDP1 | |
| SCHEMBL15730538 | 0.72 | LMNA (0.56) | LMNATSHRGAANPSR1TDP1 | |
| SCHEMBL17616497 | 0.70 | LMNA (0.49) | LMNATSHRGAANPSR1TDP1 | |
| SCHEMBL20631148 | 0.69 | PTGS2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3399968-B1 | SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE | CS PHARMATECH LTD (KY) | 2021-10-20 | — | — | EP | disclosed |