Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574042 | 0.85 | MAPT (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL30538675 | 0.85 | NPC1 (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL29354111 | 0.85 | MAPT (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL18240065 | 0.85 | NPC1 (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL11611431 | 0.85 | NPC1 (0.64) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL131175 | 0.85 | MAPT (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL2915566 | 0.85 | NPC1 (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL1389297 | 0.85 | NPC1 (1.00) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL11748662 | 0.83 | NPC1 (0.94) | SMN1; SMN2MAPTLMNARAB9ANPC1 | |
| SCHEMBL625151 | 0.83 | MAPT (0.94) | SMN1; SMN2MAPTLMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896067-A1 | NOVEL POLYCYCLIC COMPOUND | Eutec New Materials Technology (Suzhou) Co., Ltd (CN) | 2021-10-20 | — | — | EP | disclosed |