Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282494 | 0.77 | YTHDC1 (0.37) | KDM4EALDH1A1HSD17B10L3MBTL1YTHDC1 | |
| SCHEMBL4115514 | 0.75 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10L3MBTL1CFTR | |
| SCHEMBL2518142 | 0.73 | — | — | |
| SCHEMBL22207679 | 0.67 | KMT2A (0.50) | KDM4EALDH1A1L3MBTL1MAPTGAA | |
| SCHEMBL1230868 | 0.67 | PRKCI (0.56) | KDM4ERAB9APIK3CDPKM | |
| SCHEMBL7458435 | 0.65 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10L3MBTL1YTHDC1 | |
| SCHEMBL7454034 | 0.64 | ALDH1A1 (0.37) | KDM4EALDH1A1HSD17B10CFTRMAPT | |
| SCHEMBL16636736 | 0.64 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10L3MBTL1CFTR | |
| SCHEMBL18335840 | 0.64 | CFTR (0.43) | KDM4EALDH1A1HSD17B10YTHDC1CFTR | |
| SCHEMBL18337793 | 0.64 | CFTR (0.36) | KDM4EYTHDC1CFTRPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323960-A1 | FUSED TRI-CYCLIC COMPOUND AS PDE3/PDE4 DUAL INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323960-A1 | FUSED TRI-CYCLIC COMPOUND AS PDE3/PDE4 DUAL INHIBITOR | PDE3B, PDE4A, PDE3A | KDM4E 697/4885ALDH1A1 1476/4885HSD17B10 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.