Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24306335 | 0.81 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL16847388 | 0.81 | DGAT1 (0.31) | DGAT1NPC1 | |
| SCHEMBL29961918 | 0.80 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL951764 | 0.80 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL1811528 | 0.80 | ALOX5AP (0.33) | DGAT1NPC1 | |
| SCHEMBL953734 | 0.79 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL27847519 | 0.78 | NPC1 (0.33) | DGAT1NPC1 | |
| SCHEMBL16387217 | 0.78 | NPC1 (0.36) | DGAT1NPC1 | |
| SCHEMBL19284804 | 0.78 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL953732 | 0.78 | DGAT1 (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323960-A1 | FUSED TRI-CYCLIC COMPOUND AS PDE3/PDE4 DUAL INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323960-A1 | FUSED TRI-CYCLIC COMPOUND AS PDE3/PDE4 DUAL INHIBITOR | PDE3B, PDE4A, PDE3A | DGAT1 1883/4885NPC1 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.